“Job Creation Not Job Finding”, Dr. Eric Oduro Osae, Guest Speaker During PUC’s 11th Congregation Ceremony
The era of looking for a job is passed, now is all about job creation, Dr Eric Oduro Osae urge fresh graduands at the just ended 11th graduation ceremony at Pentecost University College, Sowuotum Campus on the 14th of December,2019.
The school graduated a total number of 751 students which includes, Masters, degree, diploma and that of the certificate. Most students from this noble Institution are sought after because of the high research skills, competence and ability to convert theory to practice.
Mr Oduro in his speech said there should be a system to train students as employers and not employees. He congratulated the university for taking a lead in this great directive. Again he proposed the adaptation of “TRIPLE HELIX MODEL” which serves as a way of creating close interaction between academia, industry and government. This will go a long to improve entrepreneurial growth for effective socio-economic development.
In building an entrepreneurial culture among youths and the society at large, he explained that successive governments have to put in place several policies and programmes to expose students to the rudiments of entrepreneurship and organizational development. He added that to meet contemporary global needs, universities are required to move from “arts-based education to practised system in relation to entrepreneurship and industry.
The speaker emphasized on the need to improve relationships and linkages with industry in addition to taking advantage of government programmes such as National Builders Corps (NBCO), MASLOC, Operations of the Business Advisory Centers (BACs) TVET etc. are keys to awaken the spirit of the Graduands and the youths.
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Most Cancers cells recruit CAFs, which are crucial in shaping the malignant TME.
Activated CAFs facilitate tumor cell growth, invasiveness,
and drug resistance by depositing extracellular matrix (ECM)
and secreting cytokines, chemokines, and development factors (Gascard and
Tlsty, 2016). A seemingly easy therapeutic strategy can be to immediately goal and get rid of
CAFs. Nonetheless, current research have shown that depleting αSMA (+) fibroblasts paradoxically heightens the risk of tumor invasion or migration (Özdemir et al., 2014).
Surveys present that up to 40% of all Ulcerative colitis patients are
switching to Useful Medication care. We can use non-toxic peptides and different non-toxic
therapies to provide patients lasting remissions. We also all use a specific
ulcerative colitis food regimen for all patients and marvel why on earth non-functionally
educated medical doctors don’t join the dots regarding food regimen and symptoms.
In its SMAD pathway, TGF-β binds to type II receptors, leading to the phosphorylation of downstream R-SMADs (R-SMAD2 and R-SMAD3) (Cao and
Kyprianou, 2015). These phosphorylated R-SMADs kind complexes with cytosolic
SMAD4 and translocate to the nucleus, regulating gene expression that ends in G1 cell cycle arrest and apoptosis in early-stage PCa
cells (Jones et al., 2009). Beyond the SMAD
pathway, various non-SMAD pathways, corresponding to MAPK, c-Src,
m-TOR, RhoA, RAS, PI3K/Akt, and protein phosphatase 2A/p70s6K are additionally regulated by TGF-β.
It’s not simply that any of those peptide preps are unproven, however come up
with how much an injection prices. I’m certain that LIVV just isn’t alone but doubtless consultant of many other wellness, longevity clinics which are promoting
peptides and NAD+. Extra on the LIVV well being
club, a “cutting edge wellness center” that provides an $85,000 premium membership, and just lately a
lesser different of a $10,000 membership initiation fee and $995/month.
A 1984 study(6) aimed to gauge the potential antipyretic motion of KPV.
Rabbits were given the peptide to look at its effects on the nervous system.
The results suggested that KPV exhibited antipyretic potential,
decreasing the rabbits’ body temperature to optimal ranges.
“In phrases of the security profiles of α-MSH and its tripeptides, very few knowledge are presently available as a result of lack of toxicity studies. Nevertheless, the super-potent analog of α-MSH, [Nle4-D-Phe7]-MSH, when administrated intravenously at doses of up to zero.6 mg/kg, results in occasional gastrointestinal upset and facial flushing with out major detrimental effects. Lastly, several studies have proven that PepT1 is expressed by cancer cell sorts beyond colorectal most cancers cells,64, 65, sixty six including gastric and pancreatic cancer cells.
In distinction, mice with hPepT1 deletion had decreased tumor size and inflammation. In addition, increased hPepT1 expression was noticed in human colon tissue samples from colon most cancers sufferers, suggesting that hPepT1 may be a potential treatment for colon cancer. The examine additionally showed that the anti-inflammatory tripeptide transported by hPepT1 KPV prevented tumor formation in wild-type mice, however had no effect in mice with hPepT1 deletion. These outcomes counsel that KPV might be used to treat colorectal most cancers by way of its transport by hPepT1 [8]. KPV is a tripeptide (Lys-Pro-Val) which possesses anti-inflammatory properties nonetheless its mechanisms of motion nonetheless stay unknown. PepT1 is a di/tripeptide transporter usually expressed within the small intestine and induced in colon throughout inflammatory bowel disease (IBD).
Again, peptides are protected, there might just be a few that are unsafe for you. Young girls are more delicate to peptides than males (in general) and elderly females are even more sensitive than young women. With Out being sexist, the feminine endocrine and hormonal system is slightly extra sensitive compared to the male system. There are way more hormones at play, and even a slight change in these hormones may need dire effects.
Several analogues of this sequence have also been examined as well as disulfide bridge linked homodimers (eg (CKPV)2 [7]) which yield enhancements in the peptide’s capability to suppress NFκB exercise (reviewed [8]). Regardless Of these well documented anti-inflammatory results, the mechanism of KPV motion is poorly understood. Firstly, the KPV residues might individually or collectively bind polar or non-polar amino acid sequences uncovered on the floor of key signalling proteins. As the proline residue places an angle in the KPV peptide, complimentary interactions could occur between one, two or all three residues in a quantity of potential orientations. This mannequin can’t, nonetheless, explain the obvious specificity of KPV for the NFκB pathway because the brief peptide sequence would presumably favour multiple non-specific targets. An various hypothesis predicts that the sequence of KPV will specify its actions to a molecule within the NFκB activation pathway. KPV shows the elemental options of a minimal nuclear localisation sequence (NLS).
TB-500 just isn’t a progress issue; quite, it is a main motion regulating peptide. TB-500 (Thymosin Beta 4) has been found to play an necessary position within the safety, regeneration, and transforming of injured or damaged tissues. The gene for TB-500 (Thymosin Beta 4) has also been found to be one of many first to be upregulated after a wound occurs. We’ve found, in our personal experiences that BPC it could potentially make extra of an influence when the peptide can be used regionally where the disease is infected. If an individual has extreme colon points and takes it orally we found it not as efficient as an individual who has terminal ileum issues or ulcers on the upper GI tract.
As with any supplement, it’s good to take heed to your body and search professional advice earlier than making changes. With the best strategy, you can unlock the advantages of KPV and take your restoration to the following level. Folks with intestine problems like “leaky gut” or who want additional recovery after a bout of abdomen pain say these new capsules make a distinction. Many lifters add KPV to their routine because it helps pace up healing and decrease muscle soreness after robust workouts.
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